Some months ago I was struck by the benefits of running barefoot, and here is further argument on the same issue but for children: Why barefoot is best for children. There is similarity here with the arguments in the Michael Pollan book on food I commented on a few weeks ago: first check with our evolution and past, then think if what we are doing is a good plan. Climate change raises a similar problem in that everything evolves and changes but the rate of change has to be limited if we are to survive.
I am not against intervention with scientific understanding. An example would be arguments for Vitamin D deficiency being treated with oral supplements. In the past when people spent a lot of time outdoors the amount of Vitamin D synthesized in the skin was large by the scale of recommended supplement tablets; something like 50 to 100 times the amount you would get in one tablet from the pharmacy. I am sure we were not creating that amount of Vitamin D just to throw away, so if we are not getting much sun we should not be surprised if we have health problems if we do not take vitamin D supplements. Even with this we should be thinking what else might have been happening with sun exposure that oral supplements do not provide.